PIN1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PIN1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner. |
| Immunogen | Immunogen: Purified His-tagged PIN1 protein was used to produced this monoclonal antibody. |
| Other Names | [DOD; UBL5] |
| Gene, Accession # | [PIN1], Gene ID: 5300, NCBI: NP_006212.1, UniProt: Q13526 |
| Catalog # | MBS8558759 |
| Price | $280 |
| Order / More Info | PIN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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