Edit |   |
---|---|
Antigenic Specificity | FRS2 (Phospho-Tyr436) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436. FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways. Xu H., J. Biol. Chem. 273:17987-17990(1998).Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).Dhalluin C., Mol. Cell 6:921-929(2000). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2. |
Other Names | [SNT-1; SNT2; FGFR signalling adaptor] |
Gene, Accession # | [FRS2], Gene ID: 10818, NCBI: NP_001036020.1, UniProt: Q8WU20 |
Catalog # | MBS9405883 |
Price | $200, $255 |
Order / More Info | FRS2 (Phospho-Tyr436) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |