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Antigenic Specificity | IL12B/Il 12 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Subunit beta of interleukin 12 (IL12B), also known as interleukin 12B, or interleukin-12 subunit p40, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.Protein Function: Cytokine that can act as a growth factor for activated T and NK cells, enhance the l |
Immunogen | Immunogen: E Coli-derived rat IL12B recombinant protein (Position: M23-E250). Subcellular Localization: Secreted |
Other Names | [Interleukin-12 subunit beta] |
Gene, Accession # | [Il12b], Gene ID: 64546, NCBI: XP_006246209.1, UniProt: E9PU71 |
Catalog # | MBS1750583 |
Price | $315 |
Order / More Info | IL12B/Il 12 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |