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Antigenic Specificity | Rab11-FIP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Rab11-FIP4 antibody detects endogenous levels of total Rab11-FIP4. Function: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.Subunit Structure: Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Forms a heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with HCMV (human cytomegalovirus) g |
Immunogen | Immunogen: A synthesized peptide derived from human Rab11-FIP4 Subcellular Location: Recycling Endosome Membrane; Peripheral Membrane Protein. Note: Colocalizes with RAB11A in the endocytic recycling compartment (ERC). Tissue Specificity: Present at high level in testis (at protein level). Weakly expressed in other tissues. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (88%), Chicken (100%) |
Other Names | [Rab11 family interacting protein 4; RAB11 FIP4; Rab11 FIP4 like; RGD1305063; RP23-271B20.4] |
Gene, Accession # | [RAB11FIP4], Gene ID: 84440, NCBI: NP_001290471.2, UniProt: Q86YS3 |
Catalog # | MBS9602218 |
Price | $240, $280 |
Order / More Info | Rab11-FIP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |