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Antigenic Specificity | PTK2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.4mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK |
Immunogen | Immunogen: Recombinant protein of human PTK2B |
Other Names | [PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK] |
Gene, Accession # | [PTK2B], Gene ID: 2185, NCBI: NP_775268.1 |
Catalog # | MBS2524776 |
Price | $110, $150, $225 |
Order / More Info | PTK2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |