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Antigenic Specificity | MARK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MARK4 antibody detects endogenous levels of MARK4. Description: MARK4 a member of the CAMKL family of protein kinases. Normally expressed in neural progenitors and is re-expressed in gliomas.Function: Serine/threonine-protein kinase (PubMed:15009667, PubMed:14594945, PubMed:23666762, PubMed:23184942). Phosphorylates the microtubule-associated protein MAPT (PubMed:14594945, PubMed:23666762). Also phosphorylates the microtubule-associated proteins MAP2 and MAP4 (PubMed:14594945). Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles (PubMed:14594945, PubMed:25123532). Required for the initiation of axoneme extension during cilium assembly (PubMed:23400999). Regulates the centro |
Immunogen | Immunogen: A synthesized peptide derived from human MARK4 Subcellular Location: Cytoplasm, Cytoskeleton, Microtubule Organizing Center, Centrosome. Cytoplasm, Cytoskeleton, Microtubule Organizing Center. Cytoplasm, Cytoskeleton, Cilium Basal Body. Cytoplasm, Cytoskeleton, Cilium Axoneme. Cytoplasm. Localized at the tips of neurite-like processes in differentiated neuroblast cells. Detected in the cytoplasm and neuropil of the hippocampus. Tissue Specificity: Ubiquitous. Isoform 2 is brain-specif |
Other Names | [FLJ90097; KIAA1860; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity regulating kinase 4L; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity regulating kinase like 1; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase-like 1; MARK 4; MARK 4L; MARK L1; MARK4; MARK4 serine/threonine protein kinase; MARK4 serine/threonine protein kinase; MARK4_HUMAN; MARK4S; MARKL 1; MARKL1; Nbla00650; Putative protein product of Nbla00650] |
Gene, Accession # | [MARK4], Gene ID: 57787, NCBI: NP_001186796.1, UniProt: Q96L34 |
Catalog # | MBS9600517 |
Price | $240, $280 |
Order / More Info | MARK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |