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Antigenic Specificity | Phospho-PRKACA-S339 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the regulation of platelets in response to thrombin and collagen; maintains circulating platelets in a resting state by phosphorylating proteins in numerous platelet inhibitory pathways when in complex with NF-kappa-B |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S339 of human PRKACA |
Other Names | [PKACA; PPNAD4] |
Gene, Accession # | [PRKACA], Gene ID: 5566, NCBI: NP_002721.1, UniProt: P17612 |
Catalog # | MBS8550654 |
Price | $280 |
Order / More Info | Phospho-PRKACA-S339 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |