AKT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe serine-threonine protein kinase AKT1 is catalytically inactive inserum-starved primary and immortalized fibroblasts. AKT1 and therelated AKT2 are activated by platelet-derived growth factor. Theactivation is rapid and specific, and it is abrogated by mutations in thepleckstrin homology domain of AKT1. It was shown that the activationoccurs through phosphatidylinositol 3-kinase. In the developing nervoussystem AKT is a critical mediator of growth factor-induced neuronalsurvival. Survival factors can suppress apoptosis in a transcriptionindependentmanner by activating the serine/threonine kinase AKT1,which then phosphorylates and inactivates components of the apoptoticmachinery.
ImmunogenImmunogen: Peptide
Other Names[AKT, AKT1, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha]
Gene, Accession #[AKT1], Gene ID: 207, NCBI: BC084538, UniProt: P31749
Catalog #MBS2529527
Price$195, $270, $435
Order / More InfoAKT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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