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Antigenic Specificity | CD106 |
Clone | [MR106] |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 kappa |
Format | affinity purified |
Size | 0.05 mg, 0.1 mg |
Concentration | 500 ug/ml |
Applications | Flow Cytometry (FC/FACS), Functional Assay, Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The MR106 monoclonal antibody reacts with rat CD106, a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin alpha 4 beta1 and Integrin alpha 4 beta 7 and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response. |
Immunogen | n/a |
Other Names | [Mouse CD106; CD106; CD106; CD-106; CD106; VCAM1; CD 106; CD 106; CD-106] |
Gene, Accession # | [CD106] |
Catalog # | MBS5309267 |
Price | $215, $305 |
Order / More Info | CD106 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |