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Antigenic Specificity | DAB2IP |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon (IFN) or lipopolysaccharide (LPS). Modulates the balance between phosphatidylinositol 3-kinase (PI3K)-AKT-mediated cell survival and apoptosis stimulated kinase (MAP3K5)-JNK signaling pathways; sequ |
Immunogen | n/a |
Other Names | [Purified Mouse (Mab); Disabled homolog 2-interacting protein; DAB2 interaction protein; DAB2-interacting protein; ASK-interacting protein 1; AIP-1; DOC-2/DAB-2 interactive protein; DAB2IP; AF9Q34; AIP1; KIAA1743] |
Gene, Accession # | [DAB2IP], Gene ID: 153090, NCBI: NP_115941.2, UniProt: Q5VWQ8 |
Catalog # | MBS9216857 |
Price | $165, $370 |
Order / More Info | DAB2IP Antibody from MYBIOSOURCE INC. |
Product Specific References | Chen H.,et al.Genomics 79:573-581(2002). von Bergh A.R.M.,et al.Genes Chromosomes Cancer 39:324-334(2004). Nagase T.,et al.DNA Res. 7:347-355(2000). Nakajima D.,et al.DNA Res. 9:99-106(2002). Humphray S.J.,et al.Nature 429:369-374(2004). |