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Antigenic Specificity | BMP4 |
Clone | [26H16] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human BMP4. Detects bands of ~54kDa, ~42kDa and ~23kDa by Western blot. Bone morphogenic protein 4 (BMP4) is a member of the TGF-beta superfamily that plays a critical role in mammalian mesenchymal development, influencing hematopoeisis and osteoblast differentiation and function. BMP-4 is secreted as 54 kDa inactive precursor peptides that dimerize and are activated following cleavage by members of the proprotein convertase family. Active BMP-4 binds type I and type II serine/threonine kinase receptors which signal via phosphorylation of Smad family proteins. BMP-4 and the highly homologous BMP-2 are functional orthologues of the decapentaplegic (dpp) gene in Drosophila that regulates embryonic leg and wing imaginal disc pattern |
Immunogen | Immunogen: Recombinant full length human BMP4. |
Other Names | [BMP4], [BMP4; BMP4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP2B; DVR4; BMP-4; BMP-2B] |
Gene, Accession # | [Bone morphogenetic protein], Gene ID: 652, NCBI: P12644.1, UniProt: P12644 |
Catalog # | MBS565106 |
Price | $400 |
Order / More Info | BMP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |