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Antigenic Specificity | TNF12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TNF12 protein. Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).Marsters S.A., Curr. Biol. 8:525-528(1998).Clark H.F., Genome Res. 13:2265-2270(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TNF12. |
Other Names | [Tumor necrosis factor ligand superfamily member 12; TNF-related weak inducer of apoptosis; TWEAK; APO3 ligand; Tumor necrosis factor ligand superfamily member 12] |
Gene, Accession # | [TNF12], Gene ID: 8742, NCBI: NP_003800.1, UniProt: O43508 |
Catalog # | MBS9404281 |
Price | $200, $255 |
Order / More Info | TNF12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |