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Antigenic Specificity | USP7 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: USP7 Antibody detects endogenous levels of total USP7. Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action (1, 2). Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD and JAMM enzymes. Herpesvirus-associated ubiquitin-specific protease (HAUSP, USP7) is an important deubiquitinase belonging to USP subfamily. A key HAUSP function is to bind and deubiquitinate the p53 transcription factor and an associated regulator protein Mdm2, thereby stabilizing both proteins (3, 4). In addition to regulating essential components of the p53 pathway, HAUSP also modifies other ubiquitinylated proteins such as members of the FoxO family of forkhead |
Immunogen | Immunogen: Recombinant protein of human USP7 |
Other Names | [USP7; HAUSP; TEF1] |
Gene, Accession # | [USP7], Gene ID: 7874, NCBI: NP_001308787.1, UniProt: Q93009 |
Catalog # | MBS8516401 |
Price | $290 |
Order / More Info | USP7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |