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Antigenic Specificity | Angiotensin II Receptor Type-1 (AT1 Receptor) (Extracellular) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody will recognize both rat AT1a and AT1b isoforms. Angiotensin II receptor type 1 or AT1 receptor is one of the receptors that binds the octapeptide hormone Angiotensin II (Ang II). Ang II is the peptide hormone that generates most of the known effects of the renin-angiotensin system (RAS). Ang II is generated from the angiotensinogen protein by the actions of renin, angiotensin converting enzyme (ACE) and other peptidases. Ang II has a central role in cardiovascular homeostasis by regulating vasoconstriction, renal Na+ and water readsorption. In addition, Ang II induces cell growth and proliferation and has pro-inflammatory effects. Most of the physiological actions of Ang II are mediated by AT1 receptor a member of the 7-transme |
Immunogen | Immunogen: Peptide NSSTEDGIKRIQDDC corresponding to amino acid residues 4-18 of human AT1 receptor (Accession P30556). |
Other Names | [Angiotensin II] |
Gene, Accession # | n/a |
Catalog # | MBS4157620 |
Price | $725 |
Order / More Info | Angiotensin II Receptor Type-1 (AT1 Receptor) (Extracellular) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |