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Antigenic Specificity | LTK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LTK antibody detects endogenous levels of total LTK. Function: Receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.Subunit Structure: Homodimer when bound to ligand (Probable). Part of a complex including LTK, TNK2 and GRB2, in which GRB2 promotes LTK recruitme |
Immunogen | Immunogen: A synthesized peptide Tissue Specificity: Expressed in non-hematopoietic cell lines and T-and B-cell lines. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (80%) |
Other Names | [Leukocyte receptor tyrosine kinase; Leukocyte tyrosine kinase; Leukocyte tyrosine kinase receptor; Ltk; LTK_HUMAN; Protein tyrosine kinase 1; TYK 1; TYK1] |
Gene, Accession # | [LTK], Gene ID: 4058, NCBI: NP_001129157.1, UniProt: P29376 |
Catalog # | MBS9604609 |
Price | $240, $280 |
Order / More Info | LTK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |