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Antigenic Specificity | Human UCHL1 / PGP9.5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein. UCHL1 is a member of family of proteins that hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. The expression of UCHL1 is highly specific to neurons and to cell of the diffuse neuroendocrine system and their tumors. UCHL1 exhibits both and hydrolase and a ligase activity. The S18Y variant of UCHL1, that has reduced ligase activity, has been linked to susceptibility for Parkinson's disease. |
Immunogen | Immunogen Description: Synthetic peptide from human PGP9.5 (aa171-220). |
Other Names | [UCHL1 / PGP9.5 (aa171-220) IHC-plus; UCHL1; Ubiquitin C-terminal hydrolase; PARK5; PGP9.5; PGP95; Ubiquitin thioesterase L1; Neuron cytoplasmic protein 9.5; PGP 9.5; Uch-L1; Human UCHL1; PGP9.5], [PGP9.5] |
Gene, Accession # | [UCHL1], Gene ID: 7345, NCBI: NP_004172.2, UniProt: P09936 |
Catalog # | MBS243689 |
Price | $530 |
Order / More Info | Human UCHL1 / PGP9.5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |