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Antigenic Specificity | CLK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CLK4 antibody detects endogenous levels of total CLK4. Function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine-and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.Subunit Structure: Interacts with UBL5.Post-translational Modifications: Autophosphorylates on all three types of residues.Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr |
Immunogen | Immunogen: A synthesized peptide derived from human CLK4 Subcellular Location: Nucleus. Tissue Specificity: Expressed in liver, kidney, heart, muscle, brain and endothelial cells. Predicted Cross Reactivity: Bovine, Horse, Sheep, Dog Similarity: Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [AI987988; C85119; CDC like kinase 4; CDC-like kinase 4; CLK4; CLK4_HUMAN; DKFZp686A20267; Dual specificity protein kinase CLK4; OTTMUSP00000005756; OTTMUSP00000005757; OTTMUSP00000041113; Protein serine threonine kinase Clk4; RP23-9N7.1] |
Gene, Accession # | [CLK4], Gene ID: 57396, NCBI: NP_065717.1, UniProt: Q9HAZ1 |
Catalog # | MBS9608962 |
Price | $240, $280 |
Order / More Info | CLK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |