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Antigenic Specificity | PRKAA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRKAA2 antibody detects endogenous levels of total PRKAA2. Function: Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Regulates lipid synt |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus. In response to stress, recruited by p53/TP53 to specific promoters. Predicted Cross Reactivity: Pig, Zebrafish, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Zebrafish (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [5'-AMP-activated protein kinase catalytic subunit alpha-2; AAPK2_HUMAN; ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK alpha 2 chain; AMPK subunit alpha-2; AMPK2; AMPKa2; AMPKalpha2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 catalytic subunit; Protein kinase AMP activated catalytic subunit alpha 2] |
Gene, Accession # | [PRKAA2], Gene ID: 5563, NCBI: NP_006243.2, UniProt: P54646 |
Catalog # | MBS9604170 |
Price | $240, $280 |
Order / More Info | PRKAA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |