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Antigenic Specificity | PRSS8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRSS8 antibody detects endogenous levels of PRSS8. Function: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).Subunit Structure: Heterodimer of two chains, light and heavy, held by a disulfide bond.Similarity: Belongs to the peptidase S1 family. |
Immunogen | Immunogen: A synthesized peptide derived from human PRSS8. Subcellular Location: Cell Membrane and Secreted > Extracellular Space. Found in the seminal fluid. Secreted after cleavage of its C-terminus. Tissue Specificity: Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid. Predicted Cross |
Other Names | [2410039E18Rik; AI313909; C79772; CAP1; Channel Activating Protease 1; mCAP1; Prostasin; Prostasin heavy chain; protease, serine, 8; Prss8; PRSS8_HUMAN; Serine protease 8] |
Gene, Accession # | [PRSS8], Gene ID: 5652, NCBI: NP_002764.1, UniProt: Q16651 |
Catalog # | MBS9603452 |
Price | $240, $280 |
Order / More Info | PRSS8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |