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Antigenic Specificity | NFX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of NFX1 protein. MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by NFX1 (Nuclear Transcription Factor, X-Box Binding 1) is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human NFX1 protein at amino acid sequence of 80-160 |
Other Names | [Rabbit NFX1; Transcriptional repressor NF-X1; Nuclear transcription factor, X box-binding protein 1] |
Gene, Accession # | [NFX1], Gene ID: 4799, NCBI: NP_002495.2, UniProt: Q12986 |
Catalog # | MBS9710010 |
Price | $130, $220, $325 |
Order / More Info | NFX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |