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Antigenic Specificity | BCSC-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BCSC-1 Polyclonal Antibody detects endogenous levels of BCSC-1 protein. VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human BCSC-1 at AA range: 340-420 |
Other Names | [Rabbit BCSC-1; VWA5A; BCSC1; LOH11CR2A; von Willebrand factor A domain-containing protein 5A; Breast cancer suppressor candidate 1; BCSC-1; Loss of heterozygosity 11 chromosomal region 2 gene A protein] |
Gene, Accession # | [BCSC-1], Gene ID: 4013, NCBI: NP_001123614.1, UniProt: O00534 |
Catalog # | MBS9701497 |
Price | $130, $220, $325 |
Order / More Info | BCSC-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |