Cytochrome p450 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cytochrome p450 |
| Clone | [M12P4H2] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. |
| Immunogen | Immunogen: Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence). Cellular Localization: Cytoplasmic (Endoplasmic Reticulum) |
| Other Names | [4-nitrophenol 2-hydroxylase; CPE1; CYP2Ecytochrome P450 2E1; CYPIIE1; cytochrome P450, family 2, subfamily E, polypeptide 1; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; Cytochrome P450-J; EC 1.14.13; EC 1.14.13.n7; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450C2E; P450-J; xenobiotic monooxygenase], [CYP2E1; CYP2E1; CPE1; CYP2E; P450-J; P450C2E; CYP2E] |
| Gene, Accession # | [CYP2E1], Gene ID: 1571, NCBI: NP_000764.1, UniProt: P05181 |
| Catalog # | MBS439906 |
| Price | $190, $340, $340 |
| Order / More Info | Cytochrome p450 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Itoga, S., Nomura, F., Harada, S., Tsutsumi, M., Takase, S. and Nakai, T. 1999. Mutations in the exons and exon-intron junction regions of human cytochrome P-4502E1 gene and alcoholism. Alcohol. Clin. Exp. Res. 23: 13S-16S. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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