PRMT5/Skb1Hs Methyltransferase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PRMT5/Skb1Hs Methyltransferase |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human Skb1Hs methyltransferase (also called JBP1), a homologue of yeast protein Skb1 and Hsl7p (1, 2), is composed of 637 amino acid residues and contains motifs conserved among protein methyltransferases. It methylates histones and MBP in vitro (2). Yeast Hsl7p is involved in regulation of cell cycle progression through G2 by negatively regulating Swe1p, a protein tyrosine kinase that phosphorylates and inhibits Cdc28p (3). An Hsl7p homologue, Skb1, was identified in fission yeast by virtue of its yeast two-hybrid interaction with Shk1p, a p21 (cdc42p/Rac) activated kinase (PAK) (4). Both proteins belong to the protein methyltransferase superfamily (5). Interestingly, human Skb1Hs methyltransferase was shown to interact with Jak kinases. T |
| Immunogen | Immunogen: A synthetic peptide of human PRMT5 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [HRMT1L5; IBP72; JBP1; SKB1; SKB1Hs; PRMT5; Skb1Hs Methyltransferase] |
| Gene, Accession # | [PRMT5/Skb1Hs], Gene ID: 10419, NCBI: NP_001034708.1, UniProt: O14744 |
| Catalog # | MBS8503796 |
| Price | $310 |
| Order / More Info | PRMT5/Skb1Hs Methyltransferase Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Gilbreth, M. et al. (1998) Proc. Natl. Acad. Sci. USA 95, 14781-14786. 2. Pollack, B.P. et al. (1999) J. Biol. Chem. 274, 31531-31542. 3. Ma, X.J. et al. (1996) Genes Dev. 10, 1327-1340. 4. Gilbreth, M. et al. (1996) Proc. Natl. Acad. Sci. USA 93, 13802-13807. 5. Ma, X.J. et al. (2000) Trends Biochem. Sci. 25, 11-12. |
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MYBIOSOURCE INC.
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