Phospho-ASK1 (Ser83) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Phospho-ASK1 (Ser83) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB); ELISA (EIA); Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal antibody to detect endogenous levels of ASK 1 protein only when phosphorylated at S83 in human. ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK; MKK4 and MKK6; which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However; a catalytically inactive form of ASK1 has been shown to inhibit TNF-alpha induced apoptosis. |
| Immunogen | Immunogen: Synthesized peptide derived from human ASK 1 around the phosphorylation site of S83; (20-100aa) |
| Other Names | [Mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5], [MAP3K5] |
| Gene, Accession # | [ASK1], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683 |
| Catalog # | MBS846119 |
| Price | $335 |
| Order / More Info | Phospho-ASK1 (Ser83) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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