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Antigenic Specificity | NUS1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NUS1 |
Other Names | [dehydrodolichyl diphosphate synthase complex subunit NUS1; Nogo-B receptor; dehydrodolichyl diphosphate synthase complex subunit NUS1; NUS1 dehydrodolichyl diphosphate synthase subunit; Nuclear undecaprenyl pyrophosphate synthase 1 homolog] |
Gene, Accession # | [NUS1], Gene ID: 116150, NCBI: NP_612468.1, UniProt: Q96E22 |
Catalog # | MBS3222005 |
Price | $335 |
Order / More Info | NUS1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |