NEDD4-2 Picoband Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-NEDD4-2 Picoband antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | NEDD4-2 Picoband |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Neural precursor cell expressed developmentally downregulated gene 4-like (NEDD4L) or NEDD4-2 (NEDD4-2) is an enzyme (ubiquitin ligase) of the NEDD4 family. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively |
| Immunogen | Immunogen: E Coli-derived human NEDD4-2 recombinant protein (Position: N703-D975). Subcellular Localization: Cytoplasm. Tissue Specificity: Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed: 14615060, PubMed: 15496141, PubMed: 19664597). Expressed in melanocytes (PubMed: 23999003). |
| Other Names | [E3 ubiquitin-protein ligase NEDD4-like; HECT-type E3 ubiquitin transferase NED4L; NEDD4.2; Nedd4-2; NEDD4L; KIAA0439; NEDL3] |
| Gene, Accession # | [NEDD4-2], Gene ID: 23327, NCBI: NP_001138436.1, UniProt: Q96PU5 |
| Catalog # | MBS1750676 |
| Price | $315 |
| Order / More Info | NEDD4-2 Picoband Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies