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Antigenic Specificity | DJ1/Park7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DJ1, also known as PARK7, is a soluble protein which belongs to the ThiJ/Pfp1/DJ1 superfamily. DJ1 was originally cloned as an oncogene that cooperatively transforms cells together with H-ras (1). Mutations in the DJ1 gene are associated with rare forms of autosomal recessive early-onset Parkinson's disease (2). DJ-1 is a multifunctional protein that participates in transcriptional regulation, anti oxidative stress reaction, and chaperone, protease, and mitochondrial regulation. DJ1 may also function as an sensor for oxidative stress, and it protects neurons against oxidative stress and cell death (3-5). DJ-1 is expressed in almost all cells and tissues. DJ-1 is located in the cytoplasm, nucleus, and mitochondria in cells, and secreted DJ-1 |
Immunogen | Immunogen: Full length recombinant human DJ-1 expressed in and purified from E Coli |
Other Names | [protein/nucleic acid deglycase DJ-1; Protein DJ-1; protein/nucleic acid deglycase DJ-1; Parkinsonism associated deglycase; Oncogene DJ1; Parkinson disease protein 7], [PARK7; PARK7; DJ1; DJ-1; GATD2; HEL-S-67p] |
Gene, Accession # | [DJ1/Park7], Gene ID: 11315, NCBI: NP_001116849.1, UniProt: Q99497 |
Catalog # | MBS555951 |
Price | $405 |
Order / More Info | DJ1/Park7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |