ADRBK1 (C-term), 633-660 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ADRBK1 (C-term), 633-660 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1.65 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ADRBK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 633-660 amino acids from the C-terminal region of human ADRBK1. Beta-adrenergic receptor kinase (ADRBK1), also known as GRK2, phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. ADRBK1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Heart failure is accompanied by severely impaired beta-adrenergic receptor (beta-AR) function. An important mechanism for the rapid desensitization of beta-AR function is agonist-stimulated receptor phosphorylation by t |
| Immunogen | n/a |
| Other Names | [Beta-adrenergic receptor kinase 1; Beta-ARK-1; G-protein coupled receptor kinase 2; ADRBK1; BARK; BARK1; GRK2] |
| Gene, Accession # | [ADRBK1], Gene ID: 156, NCBI: NP_001610.2, UniProt: P25098 |
| Catalog # | MBS9202173 |
| Price | $165, $370 |
| Order / More Info | ADRBK1 (C-term), 633-660 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li, J., et al., J. Biol. Chem. 278(32):30219-30226 (2003). Wan, K.F., et al., J. Biol. Chem. 278(20):18658-18663 (2003). Yang, X.L., et al., World J. Gastroenterol. 9(4):800-803 (2003). Hagen, S.A., et al., Anesthesiology 98(2):343-348 (2003). Eichmann, T., et al., J. Biol. Chem. 278(10):8052-8057 (2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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