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Antigenic Specificity | Noxa |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
Immunogen | Immunogen: A synthesized peptide derived from human Noxa. Subcellular Localization: Mitochondrion. Tissue Specificity: Highly expressed in adult T-cell leukemia cell line. |
Other Names | [Phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; Immediate-early-response protein APR; Protein Noxa; PMAIP1; NOXA], [PMAIP1; PMAIP1; APR; NOXA; NOXA; PMA-induced protein 1] |
Gene, Accession # | [PMAIP1], Gene ID: 5366, NCBI: NP_066950.1, UniProt: Q13794 |
Catalog # | MBS179822 |
Price | $160, $340, $340 |
Order / More Info | Noxa Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |