Noxa Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNoxa
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg, 0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPromotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
ImmunogenImmunogen: A synthesized peptide derived from human Noxa. Subcellular Localization: Mitochondrion. Tissue Specificity: Highly expressed in adult T-cell leukemia cell line.
Other Names[Phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; Immediate-early-response protein APR; Protein Noxa; PMAIP1; NOXA], [PMAIP1; PMAIP1; APR; NOXA; NOXA; PMA-induced protein 1]
Gene, Accession #[PMAIP1], Gene ID: 5366, NCBI: NP_066950.1, UniProt: Q13794
Catalog #MBS179822
Price$160, $340, $340
Order / More InfoNoxa Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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