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Antigenic Specificity | BCR - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against BCR-ABL1. It was validated on Western BlotTarget Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human BCR |
Other Names | [breakpoint cluster region protein isoform 1; Breakpoint cluster region protein; breakpoint cluster region protein; BCR activator of RhoGEF and GTPase; Renal carcinoma antigen NY-REN-26] |
Gene, Accession # | [BCR], Gene ID: 613, NCBI: NP_004318.3, UniProt: P11274 |
Catalog # | MBS3219161 |
Price | $335 |
Order / More Info | BCR - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |