BCR - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBCR - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against BCR-ABL1. It was validated on Western BlotTarget Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human BCR
Other Names[breakpoint cluster region protein isoform 1; Breakpoint cluster region protein; breakpoint cluster region protein; BCR activator of RhoGEF and GTPase; Renal carcinoma antigen NY-REN-26]
Gene, Accession #[BCR], Gene ID: 613, NCBI: NP_004318.3, UniProt: P11274
Catalog #MBS3219161
Price$335
Order / More InfoBCR - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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