CytokeRatin 13 / KeRatin K13 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCytokeRatin 13 / KeRatin K13
Clone[1C7]
Host SpeciesMouse
Reactive Specieshuman, zebrafish
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) (frozen), Western Blot (WB)
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DescriptionSpecificity: 1C7 reacts exclusively with cytokeRatin 13 which is present in non-cornified squamous epithelia, except cornea, and transitional epithelial regions, with the exception of basal cell layers of some stRatified epithelia. CytokeRatins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual Human cytokeRatins are numbered 1 to 20. The various epithelia in the Human body usually express cytokeRatins which are not only characteristic of the type of epithelium, but also related to the degree of
ImmunogenSource Note: 1C7 is a Mouse monoclonal IgG2a antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with a cytokeRatin prepaRation extracted from Human esophagus.
Other Names[cytokeratin 13; Keratin, type I cytoskeletal 13; keratin, type I cytoskeletal 13; CK-13; keratin-13; cytokeratin 13; cytokeratin-13; keratin 13; Cytokeratin-13; CK-13; Keratin-13], [KRT13; KRT13; K13; CK13; MGC3781; MGC161462; KRT13]
Gene, Accession #Gene ID: 3860, UniProt: P13646
Catalog #MBS570073
Price$415
Order / More InfoCytokeRatin 13 / KeRatin K13 Antibody from MYBIOSOURCE INC.
Product Specific Referencesvan Muijen, G. N., Ruiter, D. J., Franke, W. W., Achtstatter, T., Haasnoot, W. H., Ponec, M., and Warnaar, S. O. (1986). Cell type heterogeneity of cytokeRatin expression in complex epithelia and carcinomas as demonstRated by monoclonal antibodies specific for cytokeRatins nos. 4 and 13, Exp Cell Res 162, 97-113. Weikel, W., Wagner, R., and Moll, R. (1987). Characterization of subcolumnar reserve cells and other epithelia of Human uterine cervix. DemonstRation of diverse cytokeRatin polypeptides in reserve cells, Virchows Arch B Cell Pathol Incl Mol Pathol 54, 98-110.Smedts, F., Ramaekers, F., Robben, H., Pruszczynski, M., van Muijen, G., Lane, B., Leigh, I., and Vooijs, P. (1990). Changing patterns of keRatin expression during progression of cervical intraepithelial neoplasia, Am J Pathol 136, 657-68.van Niekerk, C. C., Boerman, O. C., Ramaekers, F. C., and Poels, L. G. (1991). Marker profile of different phases in the transition of normal Human ovarian epithelium to ovarian carcinomas, Am J Pathol 138, 455-63.Smedts, F., Ramaekers, F., Troyanovsky, S., Pruszczynski, M., Link, M., Lane, B., Leigh, I., Schijf, C., and Vooijs, P. (1992). KeRatin expression in cervical cancer, Am J Pathol 141, 497-511.Bauwens, L. J., De Groot, J. C., Ramaekers, F. C., Veldman, J. E., and Huizing, E. H. (1992). Expression of intermediate filament proteins in the adult Human vestibular labyrinth, Ann Otol Rhinol Laryngol 101, 479-86.Van Niekerk, C. C., Ramaekers, F. C., Hanselaar, A. G., Aldeweireldt, J., and Poels, L. G. (1993). Changes in expression of differentiation markers between normal ovarian cells and derived tumors, Am J Pathol 142, 157-77.van Dorst, E. B., van Muijen, G. N., Litvinov, S. V., and Fleuren, G. J. (1998). The limited difference between keRatin patterns of squamous cell carcinomas and adenocarcinomas is explicable by both cell lineage and state of differentiation of tumour cells, J Clin Pathol 51, 679-84.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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