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Antigenic Specificity | GATA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GATA3 Antibody: GATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer. |
Immunogen | Immunogen: GATA3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GATA3. Buffer: GATA3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [GATA3; HDR; HDRS; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3; GATA binding protein 3], [GATA3; GATA3; HDR; HDRS] |
Gene, Accession # | [GATA3], Gene ID: 2625, NCBI: NP_001002295, UniProt: P23771 |
Catalog # | MBS150421 |
Price | $375 |
Order / More Info | GATA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |