TACE Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTACE
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-alpha is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-alpha. TNF-alpha converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bond metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGF-alpha, L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP).
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 810 of human TACE
Other Names[TACE; CD156b; Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha-converting enzyme; TNF-alpha convertase; Snake venom-like protease], [ADAM17; ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B; NISBD1; CSVP; TACE; ADAM 17]
Gene, Accession #[TACE], Gene ID: 6868, NCBI: NP_003174.3, UniProt: P78536
Catalog #MBS840173
Price$330
Order / More InfoTACE Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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