HER2/ErbB2 (8G6) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HER2/ErbB2 (8G6) |
| Clone | [8G6-1H6-2B4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous ErbB-2 proteins. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is r |
| Immunogen | Immunogen: Synthetic Peptide of HER2 |
| Other Names | [c erb B2; C erb B2/neu protein; Erb B2; HER 2] |
| Gene, Accession # | [HER2/ErbB2], Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626 |
| Catalog # | MBS4751485 |
| Price | $335 |
| Order / More Info | HER2/ErbB2 (8G6) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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