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Antigenic Specificity | DYNORPHIN B (aa1-13) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine (expected from sequence), chimpanzee (expected from sequence), dog (expected from sequence), gorilla (expected from sequence), guinea pig, hamster, horse (expected from sequence), human (expected from sequence), mouse (expected from sequence), Mous |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistology Frozen, Radioimmunoassays (RIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Dynorphin B antibody recognizes dynorphin B, an endogenous opioid peptide, also known as rimorphin with the peptide sequence Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr, derived from the sequential cleavage of pro-enkephalin B to form leumorphin which is, in turn cleaved to form dynorphin B (Devi et al. 1985). The cleavage of the dynorphin precursors to form the dynorphin neuropeptides is largely controlled by the serine protease cathepsin L which co-localizes with dynorphins in secretory vesicles of brain cortical neurons(Funkelstein et al. 2010) and prohormone convertase 2, a member of the furin, peptidate S8 family (Schwarzer 2009). Dynorphin b sequence is well conserved among mammal, avian (Youngren et al. 1993) and |
Immunogen | Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Dynorphin B (1-13) were raised by repeated immunisation of rabbits with highly purified antigen. Target Species: Pig |
Other Names | [proenkephalin-B preproprotein; Proenkephalin-B; proenkephalin-B; beta-neoendorphin-dynorphin; preprodynorphin; Beta-neoendorphin-dynorphin; PreprodynorphinCleaved into the following 9 chains:Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin; Big Dyn; Dynorphin A(1-17); Dyn-A17; Dynorphin A; Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; RimorphinAlternative name(s):Dynorphin B; Dyn-B; Dynorphin B(1-13)], [PDYN; PDYN; Big Dyn; Dyn-A17; Dynorphin A; Dyn-B] |
Gene, Accession # | Gene ID: 445529, NCBI: NP_001004040.1, UniProt: P01214 |
Catalog # | MBS222378 |
Price | $420 |
Order / More Info | DYNORPHIN B (aa1-13) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |