DYNORPHIN B (aa1-13) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDYNORPHIN B (aa1-13)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesbovine (expected from sequence), chimpanzee (expected from sequence), dog (expected from sequence), gorilla (expected from sequence), guinea pig, hamster, horse (expected from sequence), human (expected from sequence), mouse (expected from sequence), Mous
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsImmunohistology Frozen, Radioimmunoassays (RIA)
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DescriptionRabbit anti Dynorphin B antibody recognizes dynorphin B, an endogenous opioid peptide, also known as rimorphin with the peptide sequence Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr, derived from the sequential cleavage of pro-enkephalin B to form leumorphin which is, in turn cleaved to form dynorphin B (Devi et al. 1985). The cleavage of the dynorphin precursors to form the dynorphin neuropeptides is largely controlled by the serine protease cathepsin L which co-localizes with dynorphins in secretory vesicles of brain cortical neurons(Funkelstein et al. 2010) and prohormone convertase 2, a member of the furin, peptidate S8 family (Schwarzer 2009). Dynorphin b sequence is well conserved among mammal, avian (Youngren et al. 1993) and
ImmunogenBuffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Dynorphin B (1-13) were raised by repeated immunisation of rabbits with highly purified antigen. Target Species: Pig
Other Names[proenkephalin-B preproprotein; Proenkephalin-B; proenkephalin-B; beta-neoendorphin-dynorphin; preprodynorphin; Beta-neoendorphin-dynorphin; PreprodynorphinCleaved into the following 9 chains:Alpha-neoendorphin; Beta-neoendorphin; Big dynorphin; Big Dyn; Dynorphin A(1-17); Dyn-A17; Dynorphin A; Dynorphin A(1-13); Dynorphin A(1-8); Leu-enkephalin; RimorphinAlternative name(s):Dynorphin B; Dyn-B; Dynorphin B(1-13)], [PDYN; PDYN; Big Dyn; Dyn-A17; Dynorphin A; Dyn-B]
Gene, Accession #Gene ID: 445529, NCBI: NP_001004040.1, UniProt: P01214
Catalog #MBS222378
Price$420
Order / More InfoDYNORPHIN B (aa1-13) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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