Mitofusin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mitofusin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Mitofusin antibody detects endogenous levels of total Mitofusin. Function: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12475957, PubMed:12759376, PubMed:27920125, PubMed:28114303). Membrane clustering requires GTPase activity (PubMed:27920125). It may involve a major rearrangement of the coiled coil domains (PubMed:27920125, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12475957, PubMed:12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:12759376). Has low GTPase activity (PubMed:27920125, PubMed:28114303).Subu |
| Immunogen | Immunogen: A synthesized peptide derived from human Mitofusin Subcellular Location: Cytoplasm and Mitochondrion Outer Membrane. Tissue Specificity: Detected in kidney and heart (at protein level) (PubMed:12759376). Ubiquitous (PubMed:11950885, PubMed:12759376). Expressed at slightly higher level in kidney and heart (PubMed:12759376). Isoform 2 may be overexpressed in some tumors, such as lung cancers (PubMed:11751411). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity |
| Other Names | [Fzo homolog; Hfzo1; Hfzo2; MFN 1; Mfn1; MFN1_HUMAN; Mitochondrial transmembrane GTPase Fzo 1; Mitochondrial transmembrane GTPase FZO 2; Mitochondrial transmembrane GTPase FZO1B; Mitofusin 1; Mitofusin-1; Mitofusin1; MS996; Putative transmembrane GTPase; Transmembrane GTPase MFN1] |
| Gene, Accession # | [MFN1], Gene ID: 55669, NCBI: NP_284941.2, UniProt: Q8IWA4 |
| Catalog # | MBS9608152 |
| Price | $240, $280 |
| Order / More Info | Mitofusin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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