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Antigenic Specificity | 5-HT-2C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total 5-HT-2C protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinosit |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human 5-HT-2C. |
Other Names | [5-hydroxytryptamine 2C receptor; 5H2C; 5HT-1C; 5HT1C; 5HT2C] |
Gene, Accession # | [5-HT-2C], Gene ID: 3358, NCBI: NP_000859.1, UniProt: P28335 |
Catalog # | MBS9406170 |
Price | $200, $255 |
Order / More Info | 5-HT-2C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |