Lck Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLck
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mg
Concentration500 ug/ml
ApplicationsImmunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThe antibody detects 56 kDa phosphorylated Lck (Tyr505) of human, mouse and rat origins. Reactivity to other species has not been tested. Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations suggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease.
ImmunogenImmunogen: Lck antibody was raised in Rabbit using synthetic peptide corresponding to amino acids around Tyr505 of human Lck as the immunogen.
Other Names[Rabbit Lck; Lck; Lck; Phospho-Lck]
Gene, Accession #[Lck], Gene ID: 3932, NCBI: AAA59503.1
Catalog #MBS5309128
Price$735
Order / More InfoLck Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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