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Antigenic Specificity | MMP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MMP8 is a member of the family of matrix metalloproteinases. It is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic crossreactivity. MMP8 was mapped to 11q21-q22. MMP8 is an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells.1 The enzyme exhibits 58% homology to human fibroblast collagenase and has the same domain structure. It consists of a 20-residue signal peptide, and an 80-residue propeptide that is lost on autolytic activation by cleavage of an M-L bond.2 MMP8 was found to possess 57% identity with the deduced protein sequence for fibroblast collagenase with 72% chemical similarit |
Immunogen | Immunogen: MMP8 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human MMP8, different from the related rat and Rabbit sequences by three amino acids, as the immunogen |
Other Names | [Affinity Purified Rabbit MMP8; MMP8; MMP8; MMP 8; MMP-8; MMP8; Matrix Metalloproteinase 8; MMP-8; MMP 8] |
Gene, Accession # | [MMP8] |
Catalog # | MBS5312611 |
Price | $345 |
Order / More Info | MMP8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |