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Antigenic Specificity | WNT6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WNT6 antibody detects endogenous levels of total WNT6. Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.Subunit Structure: Interacts with PORCN.Post-translational Modifications: Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.Similarity: Belongs to |
Immunogen | Immunogen: A synthesized peptide derived from human WNT6 Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Tissue Specificity: Expressed in gastric cancer cell lines and gastric cancer tissues (at protein level). Detected in the apical gland region of the gastric foveolar epithelium (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (88%), Dog (100 |
Other Names | [Protein Wnt 6; Protein Wnt-6; Protein Wnt-6 precursor; Wingless type MMTV integration site family, member 6; wnt 6; Wnt6; WNT6_HUMAN] |
Gene, Accession # | [WNT6], Gene ID: 7475, NCBI: NP_006513.1, UniProt: Q9Y6F9 |
Catalog # | MBS9609358 |
Price | $240, $280 |
Order / More Info | WNT6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |