WNT6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWNT6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: WNT6 antibody detects endogenous levels of total WNT6. Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.Subunit Structure: Interacts with PORCN.Post-translational Modifications: Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.Similarity: Belongs to
ImmunogenImmunogen: A synthesized peptide derived from human WNT6 Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Tissue Specificity: Expressed in gastric cancer cell lines and gastric cancer tissues (at protein level). Detected in the apical gland region of the gastric foveolar epithelium (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (88%), Dog (100
Other Names[Protein Wnt 6; Protein Wnt-6; Protein Wnt-6 precursor; Wingless type MMTV integration site family, member 6; wnt 6; Wnt6; WNT6_HUMAN]
Gene, Accession #[WNT6], Gene ID: 7475, NCBI: NP_006513.1, UniProt: Q9Y6F9
Catalog #MBS9609358
Price$240, $280
Order / More InfoWNT6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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