AMACR (C-term), 323-351 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAMACR (C-term), 323-351
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis AMACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human AMACR. This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Immunogenn/a
Other Names[Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; AMACR]
Gene, Accession #[AMACR], Gene ID: 23600, NCBI: NP_001161067.1, UniProt: Q9UHK6
Catalog #MBS9211831
Price$165, $370
Order / More InfoAMACR (C-term), 323-351 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMurray, N.P., et al. Oncol. Rep. 24(3):687-692(2010) Sonwalkar, S.A., et al. Histopathology 56(7):900-907(2010) Lakis, S., et al. World J. Gastroenterol. 16(20):2476-2483(2010) Chen, W., et al. Mol. Biol. Rep. 36(3):423-430(2009) Mubiru, J.N., et al. Gene 327(1):89-98(2004)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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