AKT2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAKT2
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, rat
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionAKT2 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the a
Immunogenn/a
Other Names[Purified Mouse (Mab); RAC-beta serine/threonine-protein kinase; 2.7.11.1; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta; AKT2]
Gene, Accession #[AKT2], Gene ID: 208, NCBI: NP_001617.1, UniProt: P31751
Catalog #MBS9216873
Price$165, $370
Order / More InfoAKT2 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesJones P.F.,et al.Cell Regul. 2:1001-1009(1991). Cheng J.Q.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:9267-9271(1992). Ota T.,et al.Nat. Genet. 36:40-45(2004). Grimwood J.,et al.Nature 428:529-535(2004). Walker K.S.,et al.Biochem. J. 331:299-308(1998).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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