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Antigenic Specificity | Mouse Khdrbs1 (C-term), 414-443 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (predicted reactivity: chicken, human, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.46 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1. Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. |
Immunogen | n/a |
Other Names | [KH domain-containing; RNA-binding; signal transduction-associated protein 1; GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68; Khdrbs1 {ECO:0000312|MGI:MGI:893579}] |
Gene, Accession # | [Khdrbs1], Gene ID: 20218, NCBI: NP_035447.3, UniProt: Q60749 |
Catalog # | MBS9208299 |
Price | $165, $370 |
Order / More Info | Mouse Khdrbs1 (C-term), 414-443 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sette, C., et al. J. Androl. 31(1):66-74(2010) Maroni, P., et al. Mol. Cell. Endocrinol. 309 (1-2), 26-31 (2009) : Paronetto, M.P., et al. J. Cell Biol. 185(2):235-249(2009) Huot, M.E., et al. Mol. Cell. Biol. 29(7):1933-1943(2009) Rajan, P., et al. BMC Cell Biol. 10, 82 (2009) : |