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Antigenic Specificity | Collagen IV |
Clone | 8E5 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous Collagen IV protein. COL4A1 (collagen type IV alpha 1 chain) encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. COL4A1 shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic a |
Immunogen | Immunogen: Synthetic Peptide of Collagen IV |
Other Names | [Mouse Collagen IV Mouse (8E5); Collagen alpha-1(IV) chain [Cleaved into: Arresten]] |
Gene, Accession # | NCBI: NP_001836.2, UniProt: P02462 |
Catalog # | MBS9700592 |
Price | $130, $220, $325 |
Order / More Info | Collagen IV Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |