Collagen IV Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCollagen IV
Clone8E5
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC) Paraffin, Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous Collagen IV protein. COL4A1 (collagen type IV alpha 1 chain) encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. COL4A1 shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic a
ImmunogenImmunogen: Synthetic Peptide of Collagen IV
Other Names[Mouse Collagen IV Mouse (8E5); Collagen alpha-1(IV) chain [Cleaved into: Arresten]]
Gene, Accession #NCBI: NP_001836.2, UniProt: P02462
Catalog #MBS9700592
Price$130, $220, $325
Order / More InfoCollagen IV Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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