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Antigenic Specificity | CD20 [10F381 (rituximab)] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg, 1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD20 (Human B-lymphocyte-restricted differentiation antigen, Bp35), is a hydrophobic transmembrane protein with a molecular weight of approximately 35 kDa located on pre-B and mature B lymphocytes, and most B-cell non-Hodgkin's lymphomas, but is not found on stem cells, pro-B cells, normal plasma cells or other normal tissues. Recombinant monoclonal antibody to CD20. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody 10F381 (rituximab). This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
Immunogen | Immunogen: Human lymphoblastoid cell line SB. Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
Other Names | [B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35 Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD20], [MS4A1; MS4A1; CD20; CD20] |
Gene, Accession # | [CD20], Gene ID: 485430 |
Catalog # | MBS488082 |
Price | $375, $1410 |
Order / More Info | CD20 [10F381 (rituximab)] Antibody from MYBIOSOURCE INC. |
Product Specific References | Reff ME, Carner K, Chambers KS, Chinn PC, Leonard JE, Raab R, Newman RA, Hanna N, Anderson DR. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood. 1994 Jan 15; 83(2):435-45. PMID:7506951 |