Edit |   |
---|---|
Antigenic Specificity | PAK5/6 (Phospho-Ser602/Ser560) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor t |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6. |
Other Names | [PAK5; PAK 6; kinase PAK6] |
Gene, Accession # | [PAK5/6], Gene ID: 57144, NCBI: NP_065074.1, UniProt: Q9P286 |
Catalog # | MBS9405451 |
Price | $200, $255 |
Order / More Info | PAK5/6 (Phospho-Ser602/Ser560) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |