PSEN1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPSEN1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of total PSEN1 antibody. Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer disease, probably due to presenilin's associated g-secretase activity for amyloid-b protein processing (1,2). Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (~20, 22, 23 kDa) fragments (CTF) (2,3).
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human PSEN1.
Other Names[PSEN1; AD3; FAD; PS-1; PS1; S182]
Gene, Accession #[PSEN1], Gene ID: 5663, NCBI: NP_000012.1, UniProt: P49768
Catalog #MBS9414991
Price$255
Order / More InfoPSEN1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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