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Antigenic Specificity | ZFYVE20 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZFYVE20 antibody detects endogenous levels of total ZFYVE20. Function: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388).Subunit Structure: Interacts with EHD1, R |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Early endosome membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (91%), Sheep (91%), Rabbit (91%), Dog (100%), Chicken (91%) |
Other Names | [110 kDa protein; FYVE finger containing Rab5 effector protein Rabenosyn 5; FYVE finger-containing Rab5 effector protein rabenosyn-5; Rabenosyn-5; RBNS5_HUMAN; Zfyve20; zinc finger FYVE domain containing 20; Zinc finger FYVE domain-containing protein 20] |
Gene, Accession # | [ZFYVE20], Gene ID: 64145, NCBI: NP_001289307.1, UniProt: Q9H1K0 |
Catalog # | MBS9605827 |
Price | $240, $280 |
Order / More Info | ZFYVE20 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |