Rb1 (Tumor Suppressor Protein) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Rb1 (Tumor Suppressor Protein) |
| Clone | [RB1/2313R] |
| Host Species | Rabbit |
| Reactive Species | human, mouse. |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma. |
| Immunogen | Immunogen: Recombinant full-length human Rb1 protein Cellular Localization: Nuclear |
| Other Names | [OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein] |
| Gene, Accession # | [Rb1], Gene ID: 5925, NCBI: NP_000312.2, UniProt: P06400 |
| Catalog # | MBS4380201 |
| Price | $190, $340, $340 |
| Order / More Info | Rb1 (Tumor Suppressor Protein) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bartek J, et. al. Oncogene 7:101-108, 1992. Grand et al. 1989. Oncogene. 4(11):1291-8. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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