ZWINT Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ZWINT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for ZW10 interactor (ZWINT) detection. Background: ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ZWINT gene. This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Immunogen: E Coli-derived human ZWINT recombinant protein (Position: Q29-Q249). Human ZWINT shares 58% and 57.1% amino acid (aa) sequence identity with mouse and rat ZWINT, respectively. |
| Other Names | [HZwint 1; HZwint1; KNTC 2 AP; KNTC2AP; ZWINT 1; ZWINT; Zwint-1; ZWINT1; O95229; ZW10 interactor; ZW10 interacting kinetochore protein], [ZWINT; ZWINT; SIP30; ZWINT1; KNTC2AP; HZwint-1; Zwint-1] |
| Gene, Accession # | [ZWINT], Gene ID: 11130, NCBI: NP_001005413.1, UniProt: O95229 |
| Catalog # | MBS178518 |
| Price | $315 |
| Order / More Info | ZWINT Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: ZWINT ZW10 interactor.2. Obuse C, Iwasaki O, Kiyomitsu T, Goshima G, Toyoda Y, Yanagida M (Nov 2004). A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nature Cell Biology 6 (11): 1135-41.3. van Vlijmen T, Vleugel M, Evers M, Mohammed S, Wulf PS, Heck AJ, Hoogenraad CC, van der Sluijs P (Aug 2008). A unique residue in rab3c determines the interaction with novel binding protein Zwint-1. FEBS Letters 582 (19): 2838-42. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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